Inhibition of the Survival of Lymphoma by Cyclohexenone Compounds from Antrodia Camphorata

摘要

The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3 -dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6, 10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of Antrodia camphorata, which can be applied for inhibiting the survival of lymphoma cells and be used as a pharmaceutical composition to inhibit the lymphoma tumor growth.

主权项

1. A method of inhibiting the survival of lymphoma cells, comprising administering to a subject in need thereof an effective amount of a compound having the following formula: wherein X and Y is oxygen, nitrogen or sulfur, R1, R2 and R3 are each a hydrogen atom, methyl or (CH2)m-CH3, and m=1-12; n=1-12.