发明名称 METHODS FOR INHIBITION OF SHC-1/P66 TO COMBAT AGING-RELATED DISEASES
摘要 The present invention relates to methods of treating one or more symptoms of a SHC-1/p66-related disease, inhibiting ROS generation or for the manufacture of a medicament in the above-mentioned treatment.
申请公布号 US2014179774(A1) 申请公布日期 2014.06.26
申请号 US201213727387 申请日期 2012.12.26
申请人 INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 发明人 CHANG Shau-Feng;MA Chun-Hsien;YANG Kuo-Yi
分类号 C07D407/10 主分类号 C07D407/10
代理机构 代理人
主权项 1. A method of treating one or more symptoms of a SHC-1/p66-related disease selected from the group consisting of aging, diabetes, and reperfusion injuries after ischemia comprising administering a polymeric composition comprising monomer units having formula I and/or a pharmaceutically acceptable salt, solvate, or prodrug thereof: to a mammal in need thereof, wherein in Formula I, each of R1 and R2, independently, is H, alkyl, or acyl; each of R3, R4, R5, R6, and R7, independently, is H, OH, alkoxyl, or acyl; and R8 is H or a saccharide moiety; and wherein the polymerized number of the monomer ranges from 2-30, and the average molecular weight of the polymer ranges from 600-10,000.
地址 Hsinchu TW