摘要 |
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of C-C motif chemokine 23, Transmembrane glycoprotein NMB, Brain- derived neurotrophic factor, Cathepsin S, Transforming growth factor beta-2, Urokinase- type plasminogen activator, Angiopoietin-2, Matrilysin, Carcinoembryonic antigen- related cell adhesion molecule 1, Creatine kinase MB, Insulin, Immunoglobulin M, Immunoglobulin E, Macrophage migration inhibitory factor, Galectin-3, Transforming growth factor beta-3, Heparan sulfate, soluble Cadherin-3, Complement C5, Platelet factor 4, Platelet basic protein, and Stromelysin-2 as diagnostic and prognostic biomarkers in renal injuries. |