发明名称 Methods and compositions for diagnosis and prognosis of renal injury and renal failure
摘要 The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of C-C motif chemokine 23, Transmembrane glycoprotein NMB, Brain- derived neurotrophic factor, Cathepsin S, Transforming growth factor beta-2, Urokinase- type plasminogen activator, Angiopoietin-2, Matrilysin, Carcinoembryonic antigen- related cell adhesion molecule 1, Creatine kinase MB, Insulin, Immunoglobulin M, Immunoglobulin E, Macrophage migration inhibitory factor, Galectin-3, Transforming growth factor beta-3, Heparan sulfate, soluble Cadherin-3, Complement C5, Platelet factor 4, Platelet basic protein, and Stromelysin-2 as diagnostic and prognostic biomarkers in renal injuries.
申请公布号 AU2010314999(B2) 申请公布日期 2014.06.26
申请号 AU20100314999 申请日期 2010.11.05
申请人 ASTUTE MEDICAL, INC. 发明人 ANDERBERG, JOSEPH;GRAY, JEFF;MCPHERSON, PAUL;NAKAMURA, KEVIN;KAMPF, JAMES PATRICK
分类号 A61K39/395 主分类号 A61K39/395
代理机构 代理人
主权项
地址