发明名称 ISOQUINOLINONE OR QUINAZOLINONE PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS
摘要 <p>The present disclosure provides phosphatidylinositol 3-kinase (PI3K) inhibitors of formula (J), or pharmaceutically acceptable salts thereof, in which n, m, R1, R2, and R3 are as defined herein. These compounds are useful for treatment of conditions mediated by one or more P13K isoforms, such as PI3K8. The present disclosure further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions to treat conditions mediated by one or more PI3K isoforms, such as PI3Kd.</p>
申请公布号 CA2895785(A1) 申请公布日期 2014.06.26
申请号 CA20132895785 申请日期 2013.12.20
申请人 GILEAD CALISTOGA LLC 发明人 EVARTS, JERRY;PATEL, LEENA;KAPLAN, JOSHUA;TREIBERG, JENNIFER A.;PERREAULT, STEPHANE;PHILLIPS, GARY
分类号 C07D403/12;A61K31/506;A61K31/517;A61P29/00;A61P35/00;A61P37/00;C07D239/90 主分类号 C07D403/12
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