| 摘要 |
PROBLEM TO BE SOLVED: To provide a potential therapeutic agent that may ameliorate certain autoimmune diseases, including multiple sclerosis and graft-versus-host disease, and improve kidney function and survival rates under the autoimmune diseases.SOLUTION: A process includes: depleting circulating lymphocytes in a mammal by administering anti-thymocyte antibody; and then, during the course of repopulation, administering to the mammal a therapeutically effective amount of latent TGF-&bgr; and/or another agent that promotes expansion of regulatory T cells. |
