| 发明名称 |
CRYSTAL STRUCTURES OF DOLASTATIN 16, DOLAMETHYLLEUINE AND DOLAPHENVALINE, AND METHODS FOR PREPARING DOLAMETHYLLEUINE AND DOLAPHENVALINE |
| 摘要 |
The present invention relates to the crystal structures of dolastatin 16, dolamethylleuine and dolaphenvaline. The present invention also relates to processes for preparing dolamethylleuine and dolaphenvaline. The present invention further relates to computer readable medium with crystal structural data and/or information stored thereon. |
| 申请公布号 |
US2014179897(A1) |
申请公布日期 |
2014.06.26 |
| 申请号 |
US201214113682 |
申请日期 |
2012.04.25 |
| 申请人 |
Pettit George R.;Smith Thomas;Xu Jun-Ping;Herald Delbert |
发明人 |
Pettit George R.;Smith Thomas;Xu Jun-Ping;Herald Delbert |
| 分类号 |
C07K7/54;G06F19/00;C07C227/18 |
主分类号 |
C07K7/54 |
| 代理机构 |
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代理人 |
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| 主权项 |
1. A crystal comprising dolastatin 16: wherein said crystal is in space group P2(1); and said crystal has unit cell dimensions of a=10.844 (5) Å, b=16.133 (5) Å, c=16.050 (5) Å, α=90.000 (5)°, β=104.062 (5)°, γ=90.000 (5)°, V=2720.4 (17) Å3. |
| 地址 |
Paradise Valley AZ US |
