| 发明名称 |
TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAFENIB |
| 摘要 |
The present invention relates to topical ophthalmological pharmaceutical compositions containing regorafenib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof but without hydrophobic silica and its process of preparation and its use for treating ophthalmological disorders. |
| 申请公布号 |
US2014179745(A1) |
申请公布日期 |
2014.06.26 |
| 申请号 |
US201314106883 |
申请日期 |
2013.12.16 |
| 申请人 |
Bayer Healthcare LLC |
发明人 |
BOTTGER Michael;VON DEGENFELD Georges;FREUNDLIEB Julia;HIRTH-DIETRICH Claudia;KELDENICH Joerg;KLAR Jurgen;MUENSTER Uwe;OHM Andreas;RICHTER Annett;RIEDL Bernd |
| 分类号 |
A61K47/44;A61K9/00;A61K47/38;A61K47/14;A61K31/44;A61K47/10 |
主分类号 |
A61K47/44 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A topical ophthalmological pharmaceutical composition comprising regorafenib, a hydrate, solvate or pharmaceutically acceptable salt of regorafenib, or a polymorph thereof as active agent and at least one pharmaceutically acceptable vehicle wherein the composition is a suspension comprising the active agent suspended in the applicable pharmaceutically acceptable vehicle and wherein the composition does not contain hydrophobic silica. |
| 地址 |
Whippany NJ US |
