发明名称 |
THROMBOXANE RECEPTOR ANTAGONISTS |
摘要 |
The invention generally relates to compounds that function as TP antagonists for treating thrombosis and other cardiovascular, renal, or pulmonary diseases. In some embodiments, the invention provides a compound including a substituted nitro phenoxy phenyl, a sulfonylurea, and an alkyl group. In some embodiments, the invention provides a method of treating thrombosis by administering an antithrombotic compound that preferentially binds to a thromboxane receptor, has preferential binding for either TPalpha (TPα) or TPbeta (&Tgr;&Rgr;&bgr;) receptor subtype. |
申请公布号 |
WO2013156871(A3) |
申请公布日期 |
2014.06.26 |
申请号 |
WO2013IB01258 |
申请日期 |
2013.04.17 |
申请人 |
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OFIRELAND, DUBLIN |
发明人 |
KINSELLA, THERESE, B.;GUIRY, PATRICK;REID, HELEN;O'CONNOR, BARRY |
分类号 |
A61K31/00;A61K31/18;A61K31/216;A61K31/44;A61P7/02;C07C311/54;C07D213/71;C07D213/89 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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