摘要 |
Disclosed herein are compositions of GHRH agonists and peptides, and methods to treat disorders, such as ischemia and reperfusion injury. In one embodiment, a method of treating a reperfusion injury in a subject in need may involve administering a therapeutically effective amount of at least one GHRH agonist peptide to the subject. In additional embodiment, a method of promoting vasculogenesis in a mammal may involve administering a therapeutically effective amount of at least one GHRH agonist peptide to the subject. In a further embodiment, a method of promoting differentiation of mesenchymal stem cells into endothelial cells may involve contacting mesenchymal stem cells with at least one GHRH agonist peptide. |
申请人 |
UNIVERSITY OF MIAMI;U.S.A., REPRESENTED BY THE DEPARTMENT OF VETERANSAFFAIRS |
发明人 |
SCHALLY, ANDREW, V.;HARE, JOSHUA, M.;BLOCK, NORMAN, L.;GOMES, SAMIRAH, A.;KANASHIRO-TAKEUCHI, ROSEMEIRE, M. |