ALLOGENEIC AUTOPHAGOSOME-ENRICHED COMPOSITION FOR THE TREATMENT OF DISEASE
摘要
A composition, comprising: an enriched population of autophagosomes derived from a non-small cell lung carcinoma cell line, and wherein the enriched population of autophagosomes includes: one or more toll-like receptor agonists; one or more tumor antigens; and one or more damage-associated molecular pattern molecules. In this way, an off-the-shelf vaccine may be available to be administered in order to stimulate a targeted immune response in patients bearing different tumor types.
申请公布号
WO2014066507(A9)
申请公布日期
2014.06.26
申请号
WO2013US66391
申请日期
2013.10.23
申请人
UBIVAC, INC.;PROVIDENCE HEALTH & SERVICES-OREGON
发明人
HILTON, TRACI;AUNG, SANDRA;VAN DE VEN, RIENEKE;PAUSTIAN, CHRISTOPHER;MOUDGIL, TARSEM;DUBAY, CHRISTOPHER;TWITTY, CHRISTOPHER;HU, HONG-MING;FOX, BERNARD A.