BIS 2H-IMIDAZOLE-2-THIONE CHELATING AGENTS AS LIGANDS FOR RADIOPHARMACEUTICAL IN VIVO IMAGING

摘要

The present invention is in the field of radiopharmaceutical agents for in vivo imaging, which comprise a metal complex of a radiometal - either in free form or conjugated to a biological targeting molecule. The invention provides novel chelating agents based on thiones, useful for preparing such radiometal complexes and radiopharmaceuticals. The invention also provides radiometal complexes of the chelators, and their methods of preparation, plus radiopharmaceutical compositions, kits and methods of imaging.