Molecular Analysis of Tumor Samples

摘要

This invention relates to methods for diagnosing cancer, e.g., cancer of epithelial origin, by detecting the presence of tumor cells in a sample, based (at least in some embodiments) on the quantification of levels of four biomarkers, MUC1, EGFR, EpCAM, and HER2. In some embodiments, the methods are performed using diagnostic magnetic resonance (DMR), e.g., with a portable relaxometer or MR imager.

主权项

1. A method for diagnosing a tumor in a subject, the method comprising:
obtaining a sample from the subject; detecting levels of MUC-1, HER2, EGFR, and EpCAM in the sample; and comparing the levels of MUC-1, HER2, EGFR, and EpCAM in the sample to reference levels; and diagnosing cancer in a subject who has levels of MUC-1, HER2, EGFR, and EpCAM above the reference levels.