发明名称 VERAPAMIL LIKE COMPOUNDS
摘要 <p>The invention is directed to a compound, a salt or a solvate thereof according to (I) wherein R1 is an optionally branched fluoroalkyl group or [18F]fluoroalkyl group, R2, R3, R4 and R5 are eacn independently a methyl, [3H]methyl, fluoroalkyl or [18F]fluoroalkyl group, and R6 is a (R)-cyano group or a (S)-cyano group; or wherein R1 is a methyl group, and R3 is a R3 is a fluoroalkyl group or a [18F]fluoroalkyl group, R2, R4 and R5 are each independently a methyl, [3H]methyl, fluoroalkyl or [18F]fluoroalkyl group, and R6 is a (R)-cyano group or a (S)-cyano group; or wherein if R1 is hydrogen, at least one of R2, R3, R4 is an optionally branched fluoroalkyl group or [18F]fluoroalkyl group.</p>
申请公布号 WO2014098593(A1) 申请公布日期 2014.06.26
申请号 WO2013NL50925 申请日期 2013.12.19
申请人 STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN;STICHTING VU-VUMC;RIJKSUNIVERSITEIT GRONINGEN;ACADEMISCH ZIEKENHUIS GRONINGEN 发明人 RAAPHORST, RENSKE;LUURTSEMA, GERT;WINDHORST, ALBERT DIRK;LAMMERTSMA, ADRIAAN
分类号 A61K51/04;A61K31/277;C07B59/00 主分类号 A61K51/04
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