PEPTIDE STRUCTURE ANALYSIS METHOD AND DEVICE

摘要

PROBLEM TO BE SOLVED: To estimate an amino acid sequence of an original peptide at high reliability by database search on the basis of a MSspectrum obtained to a posttranslationally modified peptide.SOLUTION: The peptide structure analysis method comprises the steps of: finding a peptide ion having a modified substance desorbed on a MSspectrum of a sample to be inspected and a peptide ion subjected to modification to execute MSanalysis using them as precursors (S1 to S3); finding a pair of a product ion having a desorbed modification substance derived from a peptide and a product ion subjected to modification by comparing two MSspectra (S4); eliminating one ion for each ion pair and adding intensity of the eliminated ion to intensity of the left ion (S5); and executing an existing database search under modification conditions detected in S2 and S4 to a peak list created in this way to display an identification result being the search result (S6 to S9).