发明名称 |
Injectable silk fibroin foams and uses thereof |
摘要 |
The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein can be injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection). In some embodiments, the composition described herein comprises a compressed silk fibroin matrix, which can expand upon injection into the tissue and retain its original expanded volume within the tissue for a period of time. The compositions can be used as a filler to replace a tissue void, e.g., for tissue repair and/or augmentation, or as a scaffold to support tissue regeneration and/or reconstruction. In some embodiments, the compositions described herein can be used for soft tissue repair or augmentation. |
申请公布号 |
AU2012335122(A1) |
申请公布日期 |
2014.06.26 |
申请号 |
AU20120335122 |
申请日期 |
2012.11.09 |
申请人 |
TRUSTEES OF TUFTS COLLEGE |
发明人 |
LEISK, GARY G.;LO, TIM JIA-CHING;LI, LEI;BELLAS, EVANGELIA;KAPLAN, DAVID L. |
分类号 |
A61L27/22;A61L27/14;A61L27/40;C12N5/0789 |
主分类号 |
A61L27/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|