发明名称 |
SUBSTITUTED N-(3-(PYRIMIDIN-4-YL)PHENYL)ACRYLAMIDE ANALOGS AS TYROSINE RECEPTOR KINASE BTK INHIBITORS |
摘要 |
In one aspect, the invention relates to substituted N-(3-(pyrimidin-4- yl)phenyl)acrylamide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the BTK kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the BTK kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
申请公布号 |
WO2014055934(A3) |
申请公布日期 |
2014.06.26 |
申请号 |
WO2013US63555 |
申请日期 |
2013.10.04 |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
VANKAYALAPATI, HARIPRASAD;SORNA, VENKATASWAMY;WARNER, STEVEN L.;BEARSS, DAVID J.;SHARMA, SUNIL |
分类号 |
C07D239/24 |
主分类号 |
C07D239/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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