摘要 |
PROBLEM TO BE SOLVED: To provide a TRPA1 activity inhibitor effectively inhibiting activation of TRPA1, a TRPA1 activity-inhibiting method effectively inhibiting activation of TRPA1, and a skin care preparation for external use of low irritating nature to the skin. SOLUTION: The TRPA1 activity inhibitor for inhibiting TRPA1 activity comprises a carbonate ion and/or a bicarbonate ion. The TRPA1 activity inhibitor for inhibiting TRPA1 activity comprises a substance that dissociates into a carbonate ion and/or a bicarbonate ion. The TRPA1 activity-inhibiting method for inhibiting TRPA1 activity comprises bringing a carbonate ion and/or a bicarbonate ion into contact with TRPA1. The skin care preparation for external use contains ammonia and further comprises a substance that dissociates into a carbonate ion and/or a bicarbonate ion. COPYRIGHT: (C)2011,JPO&INPIT |