摘要 |
Described is a composition of ophthalmic application that contains, amongst others, a controlled-release nanoparticulated pharmaceutical system. In addition, the nanoparticulated pharmaceutical system is formed by an inorganic nano-crystalline core and one or more layers of a polyhydroxy compound and coating particles of one or more drugs, this system increasing the bioavailability and enhancing the effect of the drug over the intraocular pressure due to the nanometric or micrometric size of the aquasomes, favoring the penetration of therapeutic doses through the ocular membrane, consequently, the dose to be applied into the eye being substantially reduced, therefore reducing the side effects of the drug which would appear during the treatment. The nanoparticualated pharmaceutical system acts as a release vehicle for the drug (s), protecting, preserving and vectorizing the biological molecules of the ocular system. |