发明名称 |
Methods of refolding mammalian glycosyltransferases |
摘要 |
<p>The present invention provides methods of refolding mammalian glycosyltransferases that have been produced in bacterial cells, including glycosyltransferase mutants that have enhanced ability to be refolded, and methods to use such refolded glycosyltransferases. The invention also provides methods of refolding more than one glycosyltransferase in a single vessel, methods to use such refolded glycosyltransferases, and reaction mixtures comprising the refolded glycosyltransferases.</p> |
申请公布号 |
EP2484759(B1) |
申请公布日期 |
2014.06.25 |
申请号 |
EP20110005681 |
申请日期 |
2005.02.04 |
申请人 |
RATIOPHARM GMBH |
发明人 |
SARIBAS, SAMI;HAKES, DAVID;WILLETT, SCOTT;JOHNSON, KARL F.;BEZILA, DANIEL JAMES;DEFREES, SHAWN |
分类号 |
C12N15/00;C12N9/10;C12P1/00;C12P19/44;C12P21/02;C12Q1/48 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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