| 发明名称 | Method of detecting auto-antibodies from patients suffering from rheumatoid arthritis, a peptide and an assay kit | ||
| 摘要 | Peptides useful in determining the presence of autoantibodies in patients suffering from rheumatoid arthritis are disclosed. | ||
| 申请公布号 | US8759114(B2) | 申请公布日期 | 2014.06.24 |
| 申请号 | US201313920017 | 申请日期 | 2013.06.17 |
| 申请人 | Stichting Voor de Technische Wetenschappen | 发明人 | Van Venrooij Waltherus Jacobus Wilhelmus;Drijfhout Jan Wouter;Van Boekel Martinus Adrianus Maria;Pruijn Gerardus Jozef Maria |
| 分类号 | C07K7/08;C07K7/52;C07K7/64;G01N33/543;G01N33/564;G01N33/68 | 主分类号 | C07K7/08 |
| 代理机构 | Morrison & Ferster LLP | 代理人 | Morrison & Ferster LLP |
| 主权项 | 1. An isolated peptide comprising the amino acid sequence of the formula: (A1-A2-A3-A4-A5)-Cit-(A6)-(A7-A8-A9-A10-A11) wherein a) A1-A2-A3-A4-A5 represents the amino acid sequence KSFVW (SEQ ID NO:28), and wherein b) A6 represents an amino acid other than glycine, and wherein c) A7-A8-A9-A10-A11 represents the amino acid sequence HARPR (SEQ ID NO:50); and wherein Cit represents citrulline. | ||
| 地址 | Utrecht NL | ||