| 发明名称 | Polynucleotide delivering complex for target cell | ||
| 摘要 | The present invention provides a polynucleotide delivery system including a cationic polymer to which a rabies virus glycoprotein (RVG) peptide is bound, wherein the cationic polymer includes a biodegradable bond, and a method of delivering polynucleotides to a target cell by using the delivery system. | ||
| 申请公布号 | US8759103(B2) | 申请公布日期 | 2014.06.24 |
| 申请号 | US201113321093 | 申请日期 | 2011.08.25 |
| 申请人 | Postech Academy-Industry Foundation | 发明人 | Kim Won Jong;Hwang Do Won;Lee Dong Soo;Son Se Jin |
| 分类号 | C12N15/00;A61K47/34 | 主分类号 | C12N15/00 |
| 代理机构 | Kile Park Reed & Houtteman PLLC | 代理人 | Kile Park Reed & Houtteman PLLC |
| 主权项 | 1. A polynucleotide delivery system comprising a polyethyleneimine (PEI) to which a rabies virus glycoprotein (RVG) peptide is bound, wherein the polyethyleneimine (PEI) comprises a disulfide bond, wherein a non-peptidic polymer is further bound between the RVG peptide and the polyethyleneimine. | ||
| 地址 | Pohang-Si, Kyungsangbuk-Do KR | ||