发明名称 |
PEG-modified arginine/lysine oxidoreductase |
摘要 |
The present invention is directed to an arginine/lysine oxidoreductase modified with polyethylene glycol, a production method thereof, and methods of treating disorders responsive to a modification of amino acid levels reactive oxygen species and/or ammonium. |
申请公布号 |
US8759060(B2) |
申请公布日期 |
2014.06.24 |
申请号 |
US201314021492 |
申请日期 |
2013.09.09 |
申请人 |
|
发明人 |
Hofmann Christian J.;Lindemann Michael |
分类号 |
C12N9/02;G01N1/30;A61K38/43;A61K47/48;C12N9/96;C12N9/06 |
主分类号 |
C12N9/02 |
代理机构 |
Loza & Loza, LLP |
代理人 |
Fedrick Michael;Loza & Loza, LLP |
主权项 |
1. A conjugate comprising an L-arginine/L-lysine oxidoreductase and at least one polyethylene glycol moiety wherein the L-arginine/L-lysine oxidoreductase has the sequence of SEQ ID NO: 8.
|
地址 |
Berlin DE |