Method for detecting polymorphism at nucleotide position-1639 of VKORC1 gene, and nucleic acid probe and kit therefor

摘要

A probe for detecting a polymorphism at position −1639 of the VKORC1 gene, the probe comprising an oligonucleotide having a nucleotide sequence having a length of 10 to 50 nucleotides, which nucleotide sequence comprises the nucleotides 80 to 89 of SEQ ID NO:1 or 2 and has a homology to SEQ ID NO:1 or 2 except that the nucleotide corresponding to the nucleotide at position 80 in SEQ ID NO:1 or 2 is cytosine, which nucleotide corresponding to the nucleotide at position 80 is labeled with a fluorescent dye.

主权项

1. A probe consisting of the nucleotide sequence of SEQ ID NO: 6 where position 1 is labeled with a fluorescent dye.