Device and method for repair of urological structures

摘要

A tissue engineering construct made from a nonwoven fabric. The fabric is made from first and second staple fibers. The first staple fibers are made from a first biocompatible, bioabsorbable material, and the second staple fibers are made from a second biocompatible, bioabsorbable material. The first material has a melting temperature lower than the second material. The fabric is formed into a three-dimensional construct suitable for the repair of urinary tract structures.

主权项

1. A method of repairing a urinary structure comprising the steps of:
A. providing an acellular repair device comprising:
a nonwoven fabric, wherein said fabric comprises first and second staple fibers,wherein the first staple fibers comprise a first biocompatible, bioabsorbable material and the second staple fibers comprise a second biocompatible, bioabsorbable material,wherein the first biocompatible bioabsorbable material is poly(p-dioxanone) and the second biocompatible material comprises a polymer selected from the group consisting of poly(glycolide) and poly(glycolide-co-lactide), andwherein said fabric is formed into a three-dimensional shape having an opening and an internal cavity wherein the opening is in communication with the cavity and the cavity is suitable for urinary bladder repair; and, B. attaching the opening on the acellular repair device to a urinary bladder structure.