Alpha-MSH therapies for treatment of autoimmune disease

摘要

Methods and compositions for the enteral treatment of autoimmune disease such a multiple sclerosis with polypeptide therapeutics. Enteral therapeutics comprise monomeric alpha-MSH polypeptides such as ACTH. Therapeutic formulations of the invention may be used to reduce the incidence or severity of autoimmune disease. For instance methods for the oral treatment of multiple sclerosis with alpha-MSH and ACTH are described.

主权项

1. A method for treating or delaying the onset of a T cell mediated inflammatory autoimmune disease in a human subject comprising orally administering to the subject an effective dose of ACTH (adrenocorticotropic hormone).