发明名称 Method of normalizing a fluorescence analyzer
摘要 A method of normalizing an analyzer response value of a fluorescence analyzer is provided. The method includes measuring an excitation spectrum of the analyzer and measuring an emission sensitivity spectrum of the analyzer. Next, a normalization factor based at least in part upon the excitation spectrum of the analyzer and the emission sensitivity spectrum of the analyzer is determined. The sample is then analyzed to obtain an uncorrected analyzer response value. A normalized analyzer response value is calculated based at least in part upon the uncorrected analyzer response value and the normalization factor.
申请公布号 US8760645(B2) 申请公布日期 2014.06.24
申请号 US201113114261 申请日期 2011.05.24
申请人 IDEXX Laboratories Inc. 发明人 Misener Garland Christian;Milan James Edward;Lachapelle Robert W.
分类号 G01J3/00;G01J3/30;G01N21/25 主分类号 G01J3/00
代理机构 Carter, DeLuca, Farrell & Schmidt, LLP 代理人 Carter, DeLuca, Farrell & Schmidt, LLP
主权项 1. A method of normalizing an analyzer, the method comprising the steps of: measuring an excitation spectrum of the analyzer; determining at least one wavelength characteristic function of the excitation spectrum of the analyzer; measuring an emission sensitivity spectrum of the analyzer; determining at least one wavelength characteristic function of the emission sensitivity spectrum of the analyzer; and determining a normalization factor based at least upon the at least one wavelength characteristic function of the excitation spectrum and the at least one wavelength characteristic function of the emission sensitivity spectrum, wherein, the normalization factor is used to normalize an analyzer response value of the analyzer.
地址 Westbrook MA US