| 发明名称 | Proteins and nucleic acids from meningitis/sepsis-associated <i>Escherichia coli</i> | ||
| 摘要 | Disclosed herein are various open reading frames from a strain of E. coli responsible for neonatal meningitis (MNEC), and a subset of these that is of particular interest for preparing compositions for immunising against MNEC infections. | ||
| 申请公布号 | US8758764(B2) | 申请公布日期 | 2014.06.24 |
| 申请号 | US200611884812 | 申请日期 | 2006.02.17 |
| 申请人 | Novartis Vaccines and Diagnostics Srl;J. Craig Venter Institute | 发明人 | Masignani Vega;Moriel Danilo Gomes;Berlanda Scorza Francesco;Norais Nathalie;Fontana Maria Rita;Pizza Mariagrazia;Serino Laura;Tettelin Herve |
| 分类号 | A61K39/108;C07K14/245 | 主分类号 | A61K39/108 |
| 代理机构 | Morrison & Foerster LLP | 代理人 | Morrison & Foerster LLP |
| 主权项 | 1. A substantially purified polypeptide comprising an amino acid sequence selected from the group consisting of (a) the sequence which has at least 95% sequence identity to SEQ ID NO: 7052; and (b) a fragment of SEQ ID NO: 7052, wherein the fragment (i) includes at least 100 consecutive amino acids from SEQ ID NO: 7052; or (ii) consists of 40 or more consecutive amino acids from SEQ ID NO: 7052. | ||
| 地址 | Siena IT | ||