Electrochemical sensors

摘要

Systems and methods are provided for detecting the presence of an analyte in a sample. A solid state electrochemical sensor can include a redox active moiety having an oxidation and/or reduction potential that is sensitive to the presence of an analyte immobilized over a surface of a working electrode. A redox active moiety having an oxidation and/or reduction potential that is insensitive to the presence of the analyte can be used for reference. Voltammetric measurements made using such systems can accurately determine the presence and/or concentration of the analyte in the sample. The solid state electrochemical sensor can be robust and not require calibration or re-calibration.

主权项

1. A sensor for detecting the presence or absence of an analyte, comprising:
a first solid state electrode having a surface having immobilized thereon a layer of a first redox-active moiety, wherein the first redox-active moiety has an oxidation potential and/or a reduction potential that is sensitive to the presence of the analyte; and a second solid state electrode having a surface having immobilized thereon a layer of a second redox-active moiety and a layer of a polymeric material adjacent to the layer of the second redox-active moiety, wherein the second redox-active moiety has an oxidation potential and/or reduction potential that is sensitive to the presence of the analyte.