| 发明名称 |
Transmucosal administration of aggregated antigens |
| 摘要 |
The present invention relates to modulation of the immune response in a mammal. In particular, the invention relates to methods of inducing oral tolerance and systemic immunity in a mammal. The invention sets forth methods and compositions useful in inducing oral tolerance and systemic immunity in a mammal. |
| 申请公布号 |
US8758759(B2) |
申请公布日期 |
2014.06.24 |
| 申请号 |
US200310531805 |
申请日期 |
2003.10.17 |
| 申请人 |
Enzo Biochem, Inc. |
发明人 |
Michaels Frank |
| 分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
DiGabriele Petti, Esq. Anna D. |
| 主权项 |
1. A method of inducing tolerance to a peptide in a mammal, the method comprising transmucosally administering to the mammal a macromolecular aggregate of the peptide, thereby inducing tolerance to the peptide in the mammal, wherein the macromolecular aggregate comprises less than 21 peptide subunits.
|
| 地址 |
Farmingdale NY US |
