| 发明名称 | Cholinergic/serotoninergic receptor and uses thereof | ||
| 摘要 | The present invention describes new cholinergic/serotoninergic chimeric receptors and provides methods and compositions suitable for screening for ligands such as agonists, antagonists and allosteric modulators of α7 nicotinic acetylcholine receptors. | ||
| 申请公布号 | US8759504(B2) | 申请公布日期 | 2014.06.24 |
| 申请号 | US201213367102 | 申请日期 | 2012.02.06 |
| 申请人 | AbbVie Inc. | 发明人 | Gopalakrishnan Murali;Li Jinhe;Cassar Steven C.;Malysz John;Anderson David J.;Gubbins Earl J.;Bertrand Daniel C. |
| 分类号 | C12N15/62;G01N33/567;C07K14/705 | 主分类号 | C12N15/62 |
| 代理机构 | Michael Best & Friedrich LLP | 代理人 | Mueller Lisa V.;Michael Best & Friedrich LLP |
| 主权项 | 1. A recombinant nucleic acid encoding a cholinergic/serotoninergic chimeric receptor, wherein the nucleic acid comprises SEQ ID NO:2. | ||
| 地址 | North Chicago IL US | ||