发明名称 |
NEUROPROTECTION AND MYELIN REPAIR USING ST-1435 |
摘要 |
<p>Methods for treating neurodegeneration and/or myelination in patients are disclosed comprising treating the patient with a progestin compound which exerts binding to progesterone receptors and elicits progesterone-receptor-induced biological responses without interacting with the androgen receptor and without inducing androgen or glucocorticoid biological responses at a dosage sufficient to prevent or reduce neurodegeneration. The progestin compound preferably comprises 16-methylene-17.alpha.-acetoxy-19-norpregn-4-ene-3,20-dione, and the methods include combining the progestin compound with an estrogen compound to provide both contraception and treatment for myelin repair and neurodegeneration, and include effects on stroke and TBI.</p> |
申请公布号 |
CA2836388(A1) |
申请公布日期 |
2014.06.21 |
申请号 |
CA20132836388 |
申请日期 |
2013.12.11 |
申请人 |
THE POPULATION COUNCIL, INC. |
发明人 |
SITRUK-WARE, REGINE;SCHUMACHER, MICHAEL MARIA HELMUT;BRINTON, ROBERTA;EL-ETR, MARINE;GHOUMARI, ABDELMOUMAN;GUENNOUN, RACHIDA |
分类号 |
A61K31/567;A61K31/565;A61P25/28 |
主分类号 |
A61K31/567 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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