| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention describes a group of substituted N-phenylbipyrrolidincarboxamides of formula(I), where m equals 1 or 2; n equals to 1 or 2; p equals to 1 or 2; Ris hydrogen, (C-C)-alkyl, CF, (C-C)-alkoxy-(C-C)-alkyl; and Ris hydrogen, halogen, (C-C)-alkyl or CF; or their salt, or enantiomer, or diastereomer. In particular, compounds in accordance with the invention are modulators of H3 receptors and, therefore, are suitable for application as pharmaceutical preparations, in particular, in treatment and (or) prevention of different diseases, modulated by H3 receptors, including diseases associated with the central nervous system.EFFECT: obtained are novel compounds, possessing useful biological properties.15 cl, 1 tbl, 44 ex |
