CRYSTALLIZATION OF 1.ALPHA.-HYDROXY-2-METHYLENE-18,19-DINOR-HOMOPREGNACALCIFEROL

摘要

A method of purifying 1.alpha.-hydroxy-2-methylene-18,19-dinor-homopregnacalciferol to obtain 1.alpha.-hydroxy-2-methylene-18,19-dinor-homopregnacalciferol in crystalline form using precipitation with hexane from ethyl acetate. A method of preparing 1.alpha.-hydroxy-2-methylene-18,19-dinorhomopregnacalciferol crystals acceptable for X-ray experiment using precipitation with hexane from benzene by diffusive exchange of the solvents is also described.