发明名称 TREATING DISEASES MEDIATED BY BLOCKADE OF THE EPITHELIAL SODIUM CHANNEL WITH PYRAZINE-2-CARBOXAMIDE DERIVATIVES
摘要 A compound of Formula I;;in free or salt or solvate form, where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
申请公布号 US2014171421(A1) 申请公布日期 2014.06.19
申请号 US201414186904 申请日期 2014.02.21
申请人 Bhalay Gurdip;Budd Emma;Bloomfield Graham Charles;Collingwood Stephen Paul;Dunstan Andrew;Edwards Lee;Gedeck Peter;Howsham Catherine;Hunt Peter;Hunt Thomas Anthony;Oakley Paul;Smith Nichola 发明人 Bhalay Gurdip;Budd Emma;Bloomfield Graham Charles;Collingwood Stephen Paul;Dunstan Andrew;Edwards Lee;Gedeck Peter;Howsham Catherine;Hunt Peter;Hunt Thomas Anthony;Oakley Paul;Smith Nichola
分类号 C07D471/10;C07D519/00 主分类号 C07D471/10
代理机构 代理人
主权项
地址 Horsham GB