IMPROVED PROCESSES FOR THE ISOLATION OF 4-AMINO-3-CHLORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2-CARBOXYLIC ACID

摘要

Processes for the preparation and isolation of 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid are described. These compounds are used as herbicides. The parent carboxylic acids are conveniently prepared by the alkaline hydrolysis of either the corresponding esters or the corresponding protected N-acetylated esters. The sodium salts obtained during the hydrolysis are neutralized with formic acid to provide the carboxylic acids.