发明名称 |
Real-time assay for the detection of botulinum toxin |
摘要 |
<p>A real-time portable and rapid detection assay to identify the presence of biologically active toxins such as botulinum toxins. The proteolytic activity of BoNT/A is measured using a peptide cleavage assay, where a fluorescent substrate is cleaved by BoNT/A, resulting in increased fluorescence. This fluorescence can be monitored in real-time using a fluorescence detection instrument, such as a real-time PCR system that has been modified to implement a detection algorithm specific to the identification of the target toxin. 33 2118860.5 3/15/2013 co.</p> |
申请公布号 |
AU2013257472(A1) |
申请公布日期 |
2014.06.19 |
申请号 |
AU20130257472 |
申请日期 |
2013.11.14 |
申请人 |
SRC, INC. |
发明人 |
KENTON ARTHUR;MASSULIK, STACEY ANNE;STITES, FRANCIS LOUISE;MOSHIER, TIMOTHY FRANCES;MILLS, JEFFREY HAROLD;CHAMBERLIN, LISA HELEN;PLOCHOCKI, DEBORAH L. |
分类号 |
G01N33/542;C07K14/00;C07K14/33;C07K14/435;C12M1/34;C12Q1/37;G01N21/64;G01N33/569 |
主分类号 |
G01N33/542 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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