发明名称 N3-HETEROARYL SUBSTITUTED TRIAZOLES AND N5-HETEROARYL SUBSTITUTED TRIAZOLES USEFUL AS AXL INHIBITORS
摘要 PROBLEM TO BE SOLVED: To provide compounds being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl and in treating diseases or conditions associated with Axl activity, and methods of using the compounds.SOLUTION: This invention relates to N-heteroaryl substituted triazoles and N-heteroaryl substituted triazoles, and pharmaceutical compositions containing a compound of formula (I), as described above, as an isolated stereoisomer or mixture thereof, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.
申请公布号 JP2014111641(A) 申请公布日期 2014.06.19
申请号 JP20140024758 申请日期 2014.02.12
申请人 RIGEL PHARMACEUTICALS INC 发明人 DANE GOFF;ZHANG JING;SINGH RAJINDER;SACHA HOLLAND;YU JIAXIN;THILO HECKRODT;DING PINGYU;JOANE LITVAK
分类号 C07D401/14;A61K31/4196;A61K31/4545;A61K31/4725;A61K31/473;A61K31/496;A61K31/517;A61K31/519;A61K31/5377;A61K31/55;A61K31/551;A61P7/02;A61P9/10;A61P13/12;A61P15/00;A61P17/06;A61P19/02;A61P19/10;A61P27/02;A61P27/12;A61P29/00;A61P35/00;A61P35/02;A61P43/00;C07D403/14;C07D405/12;C07D405/14;C07D409/14;C07D413/14;C07D471/04;C07D491/048;C07D495/04;C07D519/00 主分类号 C07D401/14
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