<p>Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated WT1 antigen. Vectors, compositions and vaccines comprising one or more nucleic acid sequences that encode a mutated WT1 antigen are disclosed. Methods of treating an individual who has a WT1-expressing tumor and methods of preventing a WT1-expressing tumor are disclosed. Mutated WT1 antigen is disclosed.</p>
申请公布号
WO2014093886(A1)
申请公布日期
2014.06.19
申请号
WO2013US75127
申请日期
2013.12.13
申请人
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;INOVIO PHARMACEUTICALS, INC.;WEINER, DAVID, B.;YAN, JIAN;WALTERS, JEWELL