发明名称 NOVEL COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT
摘要 The present invention relates to a novel compound, to a pharmaceutically acceptable salt or optical isomer thereof, to a method for preparing same, and to a pharmaceutical composition for the prevention or treatment of viral diseases containing same as an active ingredient. The novel compound according to the present invention not only has low cytotoxicity but also has excellent antiviral activity against picornavirus such as coxsackievirus, enterovirus, echovirus, poliovirus and rhinovirus, and thus can be effectively used as a pharmaceutical composition for the prevention or treatment of viral diseases such as infantile paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myitis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinus infection, or otitis media.
申请公布号 WO2014092514(A1) 申请公布日期 2014.06.19
申请号 WO2013KR11668 申请日期 2013.12.16
申请人 KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;KATHOLIEKE UNIVERSITEIT LEUVEN K.U.LEUVEN R & D 发明人 JUNG, YOUNG SIK;HAN, SOO BONG;LEE, CHONG-KYO;KIM, HAE SOO;SHIN, JIN SOO;JOHAN, NEYTS;HENDRIK, JAN THIBAUT;MALPANI, YASHWARDHAN RADHAMOHAN
分类号 C07D405/12;A61K31/4025;A61P31/12;C07D409/12 主分类号 C07D405/12
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