发明名称 Methods for modulating Metastasis-Associated-in-Lung-Adenocarcinoma-Transcript-1(MALAT-1) expression
摘要 The present embodiments provide compounds and methods for reducing expression of Metastasis- Associated-in-Lung-Adenocarcinoma-Transcript-1 (MALAT-1) RNA and/or protein in an animal. Such methods are useful for treating cancer, such as colon cancer, intestinal cancer, lung cancer (e.g. non-small cell lung cancer), liver cancer, and/or prostate cancer. In various aspects, the cancer is a primary cancer.
申请公布号 AU2012358238(A1) 申请公布日期 2014.06.19
申请号 AU20120358238 申请日期 2012.12.21
申请人 ISIS PHARMACEUTICALS, INC.;FREIER, SUSAN;HSU, SSUCHENG;MACLEOD, ROBERT;MARCUSSON, ERIC;BENNETT, C. 发明人 BENNETT, C. FRANK;FREIER, SUSAN M.;MARCUSSON, ERIC G.;HSU, SSUCHENG J.;MACLEOD, ROBERT A.
分类号 C12N15/11;A61K38/28;C07H21/02 主分类号 C12N15/11
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