摘要 |
The present embodiments provide compounds and methods for reducing expression of Metastasis- Associated-in-Lung-Adenocarcinoma-Transcript-1 (MALAT-1) RNA and/or protein in an animal. Such methods are useful for treating cancer, such as colon cancer, intestinal cancer, lung cancer (e.g. non-small cell lung cancer), liver cancer, and/or prostate cancer. In various aspects, the cancer is a primary cancer. |
申请人 |
ISIS PHARMACEUTICALS, INC.;FREIER, SUSAN;HSU, SSUCHENG;MACLEOD, ROBERT;MARCUSSON, ERIC;BENNETT, C. |
发明人 |
BENNETT, C. FRANK;FREIER, SUSAN M.;MARCUSSON, ERIC G.;HSU, SSUCHENG J.;MACLEOD, ROBERT A. |