| 发明名称 |
D-Amino Acid Derivative-Modified Peptidoglycan and Methods of Use Thereof |
| 摘要 |
The present disclosure provides modified bacteria and modified peptidoglycan comprising modified D-amino acids; compositions comprising the modified bacteria or peptidoglycan; and methods of using the modified bacteria or peptidoglycan. The modified D-amino acids include a bioorthogonal functional group such as an azide, an alkyne or a norbornene group. Also provided are modified peptidoglycans conjugated to a molecule of interest via a linker. |
| 申请公布号 |
US2014170183(A1) |
申请公布日期 |
2014.06.19 |
| 申请号 |
US201314092262 |
申请日期 |
2013.11.27 |
| 申请人 |
The Regents of the University of California |
发明人 |
Bertozzi Carolyn R.;Sloan Siegrist Palmore Mary;Jewett John C.;Gordon Chelsea G.;Shieh Peyton |
| 分类号 |
C07K9/00;C12Q1/02;A61K47/48 |
主分类号 |
C07K9/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated, modified peptidoglycan comprising at least one modified D-amino acid comprising a bioorthogonal group.
|
| 地址 |
Oakland CA US |
