| 发明名称 |
ANTIBODY RECOGNIZING N-DOMAIN OF MIDKINE |
| 摘要 |
The present disclosure relates to isolated or recombinant proteins, such as antibodies, which inhibit or reduce the function of midkine (hereinafter, referred to as “MK”) for use in the treatment or prevention of midkine-related disorders. |
| 申请公布号 |
US2014170144(A1) |
申请公布日期 |
2014.06.19 |
| 申请号 |
US201214004548 |
申请日期 |
2012.03.13 |
| 申请人 |
Sakuma Sadatosi;Halasz Maria;Jones Darren |
发明人 |
Sakuma Sadatosi;Halasz Maria;Jones Darren |
| 分类号 |
C07K16/22 |
主分类号 |
C07K16/22 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating or preventing a midkine-related disorder comprising administering to a subject in need thereof an isolated or recombinant protein comprising an antigen binding domain of an antibody which specifically binds to an epitope located within the N-domain of midkine (MK) as defined by amino acid residues 1-61 of SEQ ID NO:2, wherein the protein inhibits or reduces a function of MK.
|
| 地址 |
Kanagawa JP |
