INHIBITORS OF MEMAPSIN 2 CLEAVAGE FOR THE TREATMENT OF ALZHEIMER'S DISEASE

摘要

Proteases such as memapsin 2 are important enzymes, playing roles in a variety of diseases including Alzheimer's Disease. The inventors have developed inhibitors of memapsin 2 activity and provide methods for the treatment of a neurodegenerative disorder such as Alzheimer's disease, comprising administering an effective amount of a memapsin-2 inhbitor, either alone or in combination with an additional therapeutic agent useful in the treatment of said disorder.