发明名称 |
INOSITOL PYROPHOSPHATES, AND METHODS OF USE THEREOF |
摘要 |
The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphospahte (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention relates to compounds, compositions thereof, and methods that enhance the ability of mammalian red blood cells to deliver oxygen, by delivering IHP to the cytoplasm of the red blood cells. |
申请公布号 |
US2014170127(A1) |
申请公布日期 |
2014.06.19 |
申请号 |
US201313923023 |
申请日期 |
2013.06.20 |
申请人 |
NormOxys, Inc. |
发明人 |
NICOLAU Yves Claude;LEHN Jean-Marie;FYLAKTAKIDOU Konstantina C.;GREFERATH Ruth |
分类号 |
A61K31/6615;A61K35/18;C12N5/078 |
主分类号 |
A61K31/6615 |
代理机构 |
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代理人 |
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主权项 |
1. A composition, comprising a salt complex comprising an aliphatic ammonium cation, and an anionic ligand for an allosteric site of hemoglobin, wherein the anionic ligand comprises an internal pyrophosphate ring.
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地址 |
Brighton MA US |