摘要 |
The present invention is related to a compound of formula (I): a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of leukemia, wherein X is selected from the group consisting of N-R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl. |
申请人 |
CENTOGENE AG |
发明人 |
BELLER, MATTHIAS;LUKAS, JAN;FRECH, MORTIZ;JUNGHANSS, CHRISTIAN;ROLFS, ARNDT;PEWS-DAVTYAN, ANAHIT;EISENLOEFFEL, CHRISTIAN |