| 摘要 |
PROBLEM TO BE SOLVED: To provide methods for detecting circulating tumor cells, methods for diagnosing cancer, and methods for screening drug candidate compounds for treatment of cancer, in a mammalian subject suspected of having cancer.SOLUTION: A method comprises: obtaining a test sample from blood of a subject, the test sample comprising a cell population; mounting the test sample on a substrate; detecting the presence or absence of a first marker in the test sample that selectively binds to the circulating tumor cells; detecting the presence or absence of a second marker in the test sample that binds to the cell population or a subset of the cell population; and analyzing the cell population detected by the first and second markers to identify and characterize the circulating tumor cells. |
