发明名称 |
SPIROCYCLIC MORPHINANS AND THEIR USE |
摘要 |
The application is directed to compounds of Formula (I'-&Agr;), and especially to compounds of Formula (I-A) and pharmaceutically acceptable salts and solvates thereof, wherein R1a-R5a, Y, Za are defined as set forth in the specification. The invention is also directed to use of compounds of Formula (I'-&Agr;), and especially compounds of Formula (I-A), to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain. |
申请公布号 |
WO2014091297(A1) |
申请公布日期 |
2014.06.19 |
申请号 |
WO2013IB02783 |
申请日期 |
2013.12.13 |
申请人 |
PURDUE PHARMA L.P.;GOEHRING, R., RICHARD;TAFESSE, LAYKEA;YOUNGMAN, MARK, A. |
发明人 |
GOEHRING, R., RICHARD;TAFESSE, LAYKEA;YOUNGMAN, MARK, A. |
分类号 |
C07D471/20;A61K31/437;A61P29/00 |
主分类号 |
C07D471/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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