发明名称 |
ANTI-FZD10 MONOCLONAL ANTIBODIES AND METHODS FOR THEIR USE |
摘要 |
The present invention relates generally to anti-FZD10 antibodies and to methods of using anti-FZD10 antibodies. In particular, the anti-FZD10 antibodies described herein are useful for altering one or more of survival, replication, differentiation and epithelial-to-mesenchymal cell transition of embryonic stem cells and/or for the treatment of diseases, such as a variety of cancers, associated with expression of FZD10, including as stand-alone therapies and in combination therapies with other agents. |
申请公布号 |
EP2742067(A2) |
申请公布日期 |
2014.06.18 |
申请号 |
EP20120824632 |
申请日期 |
2012.08.09 |
申请人 |
OMEROS CORPORATION |
发明人 |
CUMMINGS, W., JASON;YABUKI, MUNEHISA;LEPPARD, JOHN, BENJAMIN;WOOD, CHRISTI, L.;MAIZELS, NANCY;ALLISON, DANIEL, S.;TJOELKER, LARRY, W. |
分类号 |
C07K16/28;A61K39/395;A61P35/00 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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