| 发明名称 |
AZACYCLIC SPIRODERIVATIVES AS HSL INHIBITORS |
| 摘要 |
<p>The invention provides novel compounds having the general formula (I) wherein R1, R2 and A are as described herein, compositions including the compounds and methods of using the compounds. The compounds inhibit hormone sensitive lipase (HSL) and may be used in the treatment of diabetes, metabolic syndrome, and obesity.</p> |
| 申请公布号 |
EP2558464(B1) |
申请公布日期 |
2014.06.18 |
| 申请号 |
EP20110715201 |
申请日期 |
2011.04.12 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
ACKERMANN, JEAN;CONTE, AURELIA;HUNZIKER, DANIEL;NEIDHART, WERNER;NETTEKOVEN, MATTHIAS;SCHULZ-GASCH, TANJA;WERTHEIMER, STANLEY |
| 分类号 |
C07D471/10;A61K31/438;A61P3/00 |
主分类号 |
C07D471/10 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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