发明名称 CYCLOPROPANEAMINE COMPOUND
摘要 The present invention provides a compound having a lysine-specific demethylase 1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for cancer, and central nervous system diseases, and the like. The present invention relates to a compound represented by the formula wherein A is a hydrocarbon group or heterocyclic group optionally having substituent(s); R is H, a hydrocarbon group or heterocyclic group optionally having substituent(s); A and R are optionally bonded to each other to form a ring optionally having substituent(s); Q 1 , Q 2 , Q 3 and Q 4 are each a hydrogen atom or a substituent; Q 1 and Q 2 , and Q 3 and Q 4 , are each optionally bonded to each other to form a ring optionally having substituent(s); X is H, an acyclic hydrocarbon group or saturated cyclic group optionally having substituent(s); Y 1 , Y 2 and Y 3 are each H, a hydrocarbon group or heterocyclic group optionally having substituent(s); X and Y 1 , and Y 1 and Y 2 , are each optionally bonded to each other to form a ring optionally having substituent(s); and Z 1 , Z 2 and Z 3 are each H or a substituent, or a salt thereof.
申请公布号 EP2743256(A1) 申请公布日期 2014.06.18
申请号 EP20120821416 申请日期 2012.08.08
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 TOMITA, NAOKI;KAJII, SHIGEO;CARY, DOUGLAS ROBERT;TOMITA, DAISUKE;IMAMURA, SHINICHI;TSUCHIDA, KEN;MATSUDA, SATORU;HARA, RYUJIRO
分类号 C07C233/80;A61K31/167;A61K31/36;A61K31/366;A61K31/381;A61K31/40;A61K31/402;A61K31/4035;A61K31/404;A61K31/4184;A61K31/42;A61K31/421;A61K31/426;A61K31/428;A61K31/429;A61K31/433;A61K31/4406;A61K31/4409;A61K31/4453;A61K31/4468;A61K31/451 主分类号 C07C233/80
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