发明名称 |
CYCLOPROPANEAMINE COMPOUND |
摘要 |
The present invention provides a compound having a lysine-specific demethylase 1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for cancer, and central nervous system diseases, and the like. The present invention relates to a compound represented by the formula
wherein A is a hydrocarbon group or heterocyclic group optionally having substituent(s); R is H, a hydrocarbon group or heterocyclic group optionally having substituent(s); A and R are optionally bonded to each other to form a ring optionally having substituent(s); Q 1 , Q 2 , Q 3 and Q 4 are each a hydrogen atom or a substituent; Q 1 and Q 2 , and Q 3 and Q 4 , are each optionally bonded to each other to form a ring optionally having substituent(s); X is H, an acyclic hydrocarbon group or saturated cyclic group optionally having substituent(s); Y 1 , Y 2 and Y 3 are each H, a hydrocarbon group or heterocyclic group optionally having substituent(s); X and Y 1 , and Y 1 and Y 2 , are each optionally bonded to each other to form a ring optionally having substituent(s); and Z 1 , Z 2 and Z 3 are each H or a substituent, or a salt thereof. |
申请公布号 |
EP2743256(A1) |
申请公布日期 |
2014.06.18 |
申请号 |
EP20120821416 |
申请日期 |
2012.08.08 |
申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
TOMITA, NAOKI;KAJII, SHIGEO;CARY, DOUGLAS ROBERT;TOMITA, DAISUKE;IMAMURA, SHINICHI;TSUCHIDA, KEN;MATSUDA, SATORU;HARA, RYUJIRO |
分类号 |
C07C233/80;A61K31/167;A61K31/36;A61K31/366;A61K31/381;A61K31/40;A61K31/402;A61K31/4035;A61K31/404;A61K31/4184;A61K31/42;A61K31/421;A61K31/426;A61K31/428;A61K31/429;A61K31/433;A61K31/4406;A61K31/4409;A61K31/4453;A61K31/4468;A61K31/451 |
主分类号 |
C07C233/80 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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